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One third of patients lost 10kg or more during the treatment period

The most prominent GRD is celiac disease (CD), a T-cell-mediated autoimmune-like disorder of the small intestine triggered by the ingestion of gluten proteins in genetically predisposed individuals

In patients with serious bleeding events, conditions that increased the risk for bleeding were often present, or patients were often taking drugs that cause thrombocytopenia (other antiepileptic drugs) or affect platelet function or coagulation (e.g., aspirin, nonsteroidal anti-inflammatory drugs, selective serotonin reuptake inhibitors, or warfarin or other anticoagulant therapy)

It depends entirely on the reason youre using them

References Abiona O, Wyatt D, Koner J, Mohammed A (2022) The optimisation of carrier selection in dry powder inhaler formulation and the role of surface energetics