It can take a few weeks for your body to adjust to the new medication
Historically, this increased insulin response mediated by GLP-1 and GIP had been attributed to factors termed incretins (derived from incretion, a term used at that time to refer to a secretion that remains inside the body), hence the name incretin effect is still used today to describe the rise in insulin mediated by the action of these hormones
So I definitely endured a lot of misunderstanding (from kids and adults)
Some people experience waves of fatigue during rapid weight loss phases (months 3 through 7), but this usually resolves within days to weeks
GLP-1 receptor agonists work by mimicking the glucagon-like peptide-1 hormone, which enhances insulin secretion, suppresses glucagon release, slows gastric emptying, and reduces appetite through central nervous system pathways
This is key because weight loss is known to improve ovulation function in PCOS