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10.3389/fmolb.2021.620683 308 ZhouX

Research investigations commonly explore the peptides in experimental models examining: Peptide-receptor interaction mechanisms Cellular signalling pathway dynamics Cytoskeletal regulation systems Intracellular regulatory network modelling Comparative peptide interaction studies Molecular signalling cascade analysis Peptide-mediated biochemical processes These experimental models allow scientists to investigate molecular regulatory mechanisms influencing cellular signalling behaviour and biochemical pathway interactions

We wanted to test if our designed CRYAB constructs would react similarly

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Published veterinary research on the peptide contributed to understanding of its mechanisms and safety profile, though this animal data has not been directly replicated in human clinical trials

Long-term toxicity Continuous injection of AOD 9604 (10 mg/kg) for 8 weeks did not cause abnormal liver and kidney functions or fluctuations in blood glucose