In silico, computer-aided methods, such as QSAR and PBPK, could also be considered as a complementary tool for the estimation of the fetotoxicity of diverse drugs and chemicals when the above methods are not easily performed
doi:10.1001/jama.2022.9009 Shen S, Bethina Liu, Chad Fanti, et al
Web of Science Query String TS = (astaxanthin OR astaxantin OR Haematococcus pluvialis) AND TS = (oral administration OR oral supplement* OR dietary supplementation) AND TS = (oxidative stress OR reactive oxygen species OR inflammation OR inflammatory OR anti-inflammatory OR metabolism OR metabolic OR metabolic syndrome OR glucose OR lipid)
Results: Meta-analysis showed a statistically significant effect of curcumin on depressive symptoms (SMD: 0.65, P = 0.01, 95% CI: 1.16 to 0.13, I 2 = 93%) and anxiety symptoms (SMD: 0.22, P = 0.01, 95% CI: 0.40 to 0.05, I 2 = 0%)
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Over the years, advancements in medical technology and understanding of the circulatory system have led to the development of more sophisticated techniques and equipment for IV therapy
