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For example, intermittent hemodialysis may be impeded for several weeks owing to pigment distribution across the dialysate membrane with subsequent triggering of a colorimetric alarm designed to detect blood leaks.4 Continuous renal replacement therapy, however, is unaffected

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2 Methods 2.1 Search strategy To undertake this systematic review, an exhaustive search was carried out through the Medline, Cochrane, and Scopus databases to identify those clinical trials related to the topic until January 2022

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These could be signs of a more serious problem like a blood clot