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Journal Diabetes Research

GLP-1 receptor agonists for the reduction of atherosclerotic cardiovascular risk in patients with type 2 diabetes

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Targeting of IGF-1R to block its signalling may be obtained by interference with ligand/receptor interactions, receptor synthesis and expression, receptor TK activity, or combinations of these strategies

Controindicazioni dell'Acetil-L Carnitina Sebbene l'Acetil-L Carnitina sia generalmente sicura, pu presentare alcune controindicazioni ed effetti collaterali: Disturbi gastrointestinali: nausea, vomito, crampi addominali e diarrea

They should mainly be used as second-line therapy as add on to metformin in patients with type 2 diabetes who have no pre-existing cardiovascular disease and have a therapeutic goal to avoid hypoglycaemic events