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Ipamorelin is a selective GHS (GHRP-type) that triggers rapid GH pulses via the ghrelin/GHS-R pathway with little ACTH/cortisol stimulation

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The study further reports that exenatide injected into the interpeduncular nucleus decreased nicotine selfadministration and prevented nicotine from modulating intracranial selfstimulation threshold in rats (Tuesta et al., 2017)