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Whilst the majority of investigations into the role of testosterone in muscle adaptive response have been performed in males (reflecting male biology), the importance of circulating concentrations of testosterone in adult women should not be underestimated based on its biological role in the conversion of progesterone to the principal oestrogensoestradiol and oestrone (Cui et al., 2016), a reduction in testosterone generally does not occur independently of other hormones (such as the oestrogens) in females (e.g., following the menopause) (Chakravarti et al., 2007)

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This accelerates skin aging over time and creates repeated opportunities for irritation and infection

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This neuro-hormone could also elevate levels of antioxidant enzymes (i.e., SOD, CAT, GSH and GPx), and inhibit detrimental effects of NLRP3 inflammasome 659

Heliyon 10 , e27898 (2024)