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[223] [224] [221] Medical researcher Ivan Oransky said the errors were characteristic of generative AI usage: "They come up with references that share a lot of words and authors and even journals, journal names, but they're not real." [225] Some of the report's citation URLs contained the string "oaicite", indicating a tool produced by OpenAI was used
In 2017, Neelakantan and colleagues first systematically characterized 5amino1mq during screening for selective NNMT inhibitors, with findings published in Biochemical Pharmacology - marking the official discovery and public reporting of the compound.Through structural modification of quinolinebased precursors, the team identified 5amino1mq as a small, membranepermeable molecule with the chemical formula CHN.With an extremely low IC value, it became one of the most promising selective NNMT inhibitors available at the time, with high specificity and no significant inhibition of other metabolically relevant enzymes
Higher doses (particularly 54 mg) showed somewhat increased gastrointestinal symptoms compared to lower doses
Phylogenomic analysis of the species of the Mycobacterium tuberculosis complex demonstrates that Mycobacterium africanum, Mycobacterium bovis, Mycobacterium caprae, Mycobacterium microti and Mycobacterium pinnipedii are later heterotypic synonyms of Mycobacterium tuberculosis