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Indications Routine immunization (children & adults) Booster doses Wound management (injury with risk of tetanus) During pregnancy (to prevent neonatal tetanus) Immunization Schedule In Children Given as part of: DTaP / Pentavalent vaccine In Adults Booster every 10 years In Pregnancy 2 doses during pregnancy (if not previously immunized) Dose & Route 0.5 mL Intramuscular (IM) injection Usually in deltoid muscle (adults) Side Effects Common: Pain at injection site Redness Mild swelling Low-grade fever Rare: Severe allergic reaction (anaphylaxis) Neurological reactions (very rare) Wound Management If a patient comes with a deep wound: Doctor evaluates: Immunization history Type of wound If vaccination incomplete Tetanus toxoid + Tetanus immunoglobulin may be given

Trypsin was selected as the digestion enzyme, with a maximum allowance of two missed cleavages

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Key Features Research-Grade Quality: Produced to support high standards of purity and consistency for laboratory research purposes

Besides, current mitochondria-targeting nanomedicines mainly focus on disease treatment, but the exploration of mitochondria-targeting probes that monitor disease progression is equally important, such research is still insufficient

doi: 10.1038/s41598-024-76825-9 83 ItoJShirasunaKKuwayamaTIwataH