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Gut and systemic GLP-1 resistance have been previously described in HFD-fed mice, associated with dysglycemia, insulin resistance, increased food intake, and impaired gastric emptying, and attributed to an acquired impairment of the gut-brain axis secondary to intestinal dysbiosis (34)

T.ZhangQ.WitleyS.Blid SkldhedenS.et al (2023)

Treatment is available in all 50 states from licensed 503A compounding pharmacies, and HSA/FSA funds are eligible for coverage

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