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According to Mayo Clinic, possible effects include joint pain, swelling or fluid retention, injection-site reactions, and changes in blood sugar, and rare serious allergic reactions are possible (Mayo Clinic side effects)

Another common drug your doctor may try is triamcinolone , a type of corticosteroid solution that is injected directly into acne nodules

10.1001/jamaneurol.2013.929 [DOI] [PubMed] [Google Scholar] Gowland A., Opie-Martin S., Scott K

Introducing bacteria into the subcutaneous layer is a surefire way to cause a painful, red, and hot reaction that goes far beyond a simple burn

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