Still, high doses can act as prooxidants, meaning they might generate reactive oxygen species under certain conditions
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Hypoxia, a pathological feature of endometriosis, stabilizes EZH2 mRNA by reducing m 6 A RNA methylation through increased ALKBH5 (m 6 A demethylase) and decreased YTHDF2 (m 6 A reader), thereby enhancing EZH2 protein levels
When the body is under excessive stress, these proteins exert a protective role by lessening oxidative action of the reactive oxygen species (ROS) and a wide range of metabolic stress, including structural and functional myodamage [87, 88]
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doi.org/10.4137/CMRH.S14681 Xu Y, Nisenblat V, Lu C, et al