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Thyroid (2002) 12(10):86778

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What the mechanism does NOT prove: Demonstrating a GH pulse in a pharmacokinetic study does not establish that this translates into clinically meaningful body composition change, injury recovery, or anti-aging benefit in healthy adults over months or years

From a biochemical point of view, intracellular iron and ROS increase, leading to GSH depletion and impaired GPX4 activity

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