[2] Cell Line:PDL9 cells Concentration:25 M Incubation Time:5 days Result:Decreased the protein levels of representative senescent markers, including p16, p21, and p53
Laboratory test results show liver transaminase abnormalities, elevated prothrombin times, and elevated bilirubin, along with abnormalities in renal function test results (ie, blood urea nitrogen and creatinine)
Data Handing and Statistical Analysis Quantification of neutrophils and mast cells number in the digits and knees synovial tissue was performed with the image analysis system (AxioVision Software, Zeiss) (analyzing at least five distinct sections per mouse)
Several studies have shown that IGF-2 in the tumor microenvironment is derived mainly from CAFs and that high levels of IGF-2 inhibit the infiltration and cytotoxicity of CD8+ T cells, exacerbating the immunosuppressive effect of tumors (78,141)
The detection limit was 0.003 mg FA/g sample, and the limit of quantification (LOQ) was 0.01 mg FA/g samples
P values for unpaired comparisons between two groups with comparable variance were calculated by two-tailed Students t -test
