Understanding Semaglutide and Its Mechanism of Action Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, a class of medications designed to regulate blood sugar levels and promote weight loss
PMOS is a common endocrine and metabolic condition Raised body mass index (BMI) reduces fertility by causing hormonal imbalances, which can disrupt ovulation in women, Clare Thompson, MBBS, BSc, nMRCGP, General Practitioner at the Cadogan Clinic, where she leads the Weight Management Service, who was not involved in the study, explained to Medical News Today
Notably, the STEP (Semaglutide Treatment Effect in People with obesity) trials, which specifically examined body composition, demonstrated substantial weight loss compared with placebo (NCT03548935) [53], and reductions in fat mass and visceral adipose tissue were accompanied by decreases in lean mass, although the proportion of lean mass relative to total body mass increased (NCT04074161) [54]
They may also be preferable for those who dont like needles or prefer not to self-inject
Compounding when drugs are on FDAs drug shortages list
Camandola, S