PYY336 as an anti-obesity drug target
GLP-1 receptor agonists, such as liraglutide and semaglutide, mimic the action of the natural hormone and are commonly used to manage type 2 diabetes and promote weight loss
Nakano T, Yoshida E, Sasaki Y, Kazama S, Katami F, Aoki K, Fujie T, Du K, Hara T, Yamamoto C, Takahashi T, Fujiwara Y, Eto K, Iwakura Y, Shinoda Y, Kaji T (2024) Mechanisms underlying sensory nerve-predominant damage by methylmercury in the peripheral nervous system
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The reward centers reduce the dopamine response to food, making that slice of pizza feel less compelling
The true measure of this "resistance" is the voltage measured during the given load profile