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In agreement with the above-mentioned effects of the blockade of GCGR in BAT activation (Fig

doi: 10.1038/s41586-019-1426-6

Ma J, Cheng L, Liu H, Zhang J, Shi Y, Zeng F, Miele L, H Sarkar F, Xia J, Wang Z (2013) Genistein down-regulates miR-223 expression in pancreatic cancer cells

Nature Reviews Immunology., 7 (10), 803815

And its the difference between telling a client that costs are going up 10% and showing them three specific scenarios for bringing that number down to 6% or 7% without gutting the benefits their employees care about