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Nature Reviews Neuroscience, 13(5), 293307

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3 Within the PD-1/PD-L1 inhibitor classes, an increased rate of any-grade immune-related adverse events has been observed with PD-1 inhibitors compared with PD-L1 inhibitors

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The lower chamber was added with various materials supplemented with 10% FBS, while serum-free DMEM was added to the upper chamber