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Physiology, cortisol

The answer is noresults are not permanent

GCL is considered the speed limiting enzyme of synthesis since overexpression of GS does not increase GSH levels while overexpression of GCL increases the synthesis of GSH (61) (Figure 3)

12 Discussion To date, there are few studies demonstrating utility of topical glutathione in treating hyperpigmentation, oxidative damage, TEWL, and improving skin elasticity