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Our primary aim was to dissect the role of the incretin peptide hormone GLP-1 in this context by systemically administering GLP-1 and glucose via intraperitoneal injection

Mice were then randomized in five homogenous groups ( n = 5 per group) according to their blood glucose, HOMA-IR and body weight

Padwal R, Brocks D, Sharma AM

When tirzepatide binds to GLP-1 and GIP receptors, it sends coordinated signals that can reduce appetite, slow gastric emptying and improve insulin responseworking together to enhance overall metabolic outcomes

Exenatide decreases ER stress in response to synthetic stressors (25)

Diabetologia 47: 926936, 2004