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FDA Phase 2 trial program for obesity was discontinued without approval

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The incidence of sporadic ALS (SALS) in the 1990s in Europe and North America ranged from 1.5 to 2.7 per 100000 inhabitants per year, with an equal incidence in these regions (Wijesekera and Leigh 2009)

Independent testing has found frequent mislabeling, underdosing, or contamination