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Participants were randomized to receive weekly injections of tirzepatide at 5 mg, 10 mg, or 15 mg, or placebo, for 72 weeks

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A: Anecdotal reports vary, with some noticing changes in a week, while others may need several weeks depending on dosage and condition

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A pivotal consideration is that the weight loss achieved with these medications directly addresses the primary pathophysiological driver of MASLD