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Five SD rats died after 10 days of the administration of the ADC containing four monomer PEG chains, and no animals died within 28 days after the administration of the ADC containing 8 or 12 PEG chains

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Gastrointestinal Decontaminatio Protracted vomiting induced by ipecac may cause difficulty with the subsequent administration of activated charcoal or acetaminophen antidot Some toxicologists who feel that gastric lavage has not been proven to be helpful and should be used only if the ingestion is potentially rapidly fatal and the patient presents to the emergency department within 1 hour of the ingestion Dr

Takeaways Given the concerns about retinopathy progression, internists may also seek input from optometrists on whether GLP-1/GIP agonists should be prescribed in patients with existing retinopathy

Moeller et al