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4I), suggesting a coordinated regulation of mitochondrial glutathione and Fe-S cluster during differentiation

Conversely, TGF-RI upregulation exacerbates MASLD and fibrosis, as seen in models of SIX1 (Sine oculis homeobox homologue 1) or SHMT2 (Serine hydroxymethyl transferase 2) expression (Gao et al