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Insulin resistance was calculated by means of the homeostatic model assessment index (HOMA-IR) using the relationship between the fasting blood glucose, according to the following formula: HOMA-IR = Insulin(U/mL) Blood glucose(mM)/ 22.5

A four-strain probiotic exerts positive immunomodulatory effects by enhancing colonic butyrate production in vitro

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(SE= 0.096, p=0.00, CI [2.159-2.536]) while adjusting for potential cofounders as age, gender, CCI, patient and hospital characteristics

In the brain, it acts on appetite centers to reduce hunger and food intake, which significantly contributes to weight loss

thus we investigated if GLP-1 could modulate glucose metabolism in -cells