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Liver-targeting medications (such as resmetirom, fibroblast growth factor 21 analogs and lanifibranor), aiming at liver inflammation and collagen deposition, are expected to become crucial in individuals with more advanced liver disease [138]

This metabolic adaptation is a survival mechanism that served our ancestors well but now works against weight loss goals

J Clin Res Pediatr Endocrinol

Both medicines can cause gastrointestinal side effects

Peptides studied in metabolic medicine include GLP-1 analogs, MOTS-C, and others involved in mitochondrial function, appetite regulation, and immune signaling.

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