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Serena Williams under fire after promoting GLP-1 weight loss medication | ChicagoNOW Serena Williams is under fire from fans after she revealed she lost more than 30 pounds with the help of a GLP-1 medication

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GLP-1R works through the combination of the endogenous ligand Glucagon-like peptide-1 (GLP-1) or exogenous agonists, which activate multiple intracellular signaling pathways that enhance insulin secretion, inhibit glucagon secretion, protect -cells from apoptosis, delay gastric emptying and increase satiety

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