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5 September 2017

Hair loss rarely appears overnight

PMID 39987697

Specific inhibition of mitochondrial fatty acid oxidation by 2-bromopalmitate and its coenzyme A and carnitine esters

Clinicians should monitor thyroid function tests (TSH, free T4) at: Baseline before starting weight loss injections 6-8 weeks after achieving maintenance dose Every 3-6 months during active weight loss After significant weight stabilization Symptoms of overreplacement (palpitations, anxiety, tremor, heat intolerance) should prompt earlier testing

The MHRA-approved dosing schedule begins with 3 mg once daily for 30 days (a starter dose for tolerability that is not effective for glycaemic control), potentially increasing to 7 mg and then 14 mg based on individual response and tolerability