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GLP-1RA therapy also has been shown to enhance the redox state and mitochondrial respiration in patients with type 2 diabetes

After five washes for 10 min at RT in PBS supplemented with 0.3% Triton X-100 and 1% bovine serum albumin, sections were incubated for 1 h at RT with a secondary goat-anti-rabbit antibody (2 g/mL, Alexa Fluor 555, Molecular probes)

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SBP2 has been shown to contain a redox-active Cys, which regulates its subcellular localization and activity as oxidative conditions have been shown to sequester this protein in the nucleus and limit Sec incorporation into some selenoproteins (283)

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However, direct clinical evidence for airway-specific effects remains scarce and warrants further investigation (42)