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COA may be available depending on supplier qualification and batch status

In human neurological samples, -ketoglutarate dehydrogenase activity was studied (Mastrogiacomo and Kish, 1994

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1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2-fluoroethanone ( 13 ) Yield 48%, white crystals