Glutathione is a powerful antioxidant that helps protect cells from oxidative stress, detoxifies harmful substances, and supports immune function
Unraveling neurological drug delivery: polymeric nanocarriers for enhanced blood-brain barrier penetration
Cells can be lysed directly using denaturants such as urea or guanidine-HCl
Mitochondrial dysfunction, impaired axonal transport, and neuroinflammation are key contributors to oxidative stress in ALS [169]
Notably, methodological developments we have emphasized include transfer learning of pretrained models from large cohorts, multimodal models fusing imaging information with clinical and/or genomics, explainability techniques for the interpretation of models-e.g., saliency maps, Grad-CAM-and federated learning methods to address privacy and generalization issues across institutions
van Lennep J (Hans)PA, Trossl F, Perez RSGM, Otten RHJ, van Middendorp H, Evers AWM, et al