Most supplements to take while on GLP-1s may help negate the side effects of the drugs
Published online 16 November 2024
While once viewed as primarily drugs for treating diabetes, these therapies are now finding new markets, but putting new pressures and challenges for the healthcare system and pharmaceutical companies
Among the marketed large molecule injectable GLP-1 agonists, semaglutide, apart from weight-loss, is being studied for kidney disease and tirzepatide (a dual GLP-1 and GIP receptor agonist) is being evaluated for sleep apnea in Ph 3 clinical trials
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GLP-1 (brown ribbon representation) residue 3 (D9) (white stick) forms an ionic interaction (red dotted lines) with R1902.60, which is involved in key hydrogen bonds with N2403.43 (in turn interacting with S1862.56)