Here's the straightforward answer to the question, "Vitamin C vs Niacinamide: Which is better?" - Vitamin C: Because of its antioxidant and melanin-inhibiting qualities, dermatologists frequently advise vitamin C for sun-induced pigmentation
It is composed of three amino acids linked together into a tripeptide and is easily broken down during digestion
The individual amino acids are absorbed and can be used to resynthesize glutathione intracellularly, but this is a slow, rate-limited process that does not produce the acute plasma elevation seen with parenteral routes
It inhibits ferroptosis by inhibiting the expression of activating transcription factor 3 (ATF3), reducing the levels of lipid ROS and increasing the levels of GSH, which ultimately attenuates IRI- or FA-induced AKI [190]
However, BAs may also harm intestinal bacteria due to their toxic effects, mediating oxidative stress and DNA damage (Collins et al., 2023)
The skin also inhibits the production of melanin, the body too much so