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Improved Insulin Sensitivity and Lipid Metabolism: Secondary effects of weight loss reduce ectopic fat and systemic inflammation

The dual receptor agonism could, therefore, counteract the two pathogenetic mechanisms of T2DM (adiposity-induced insulin resistance and pancreatic insulin deficiency) more effectively than selective mono-agonists [163]

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Opioids are sometimes used to treat nerve pain, but they are usually used only if other treatments haven't worked