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Foods high in fat and sugar can lead to uncomfortable side effects like diarrhea, constipation and heartburn Image content: This image is available to view online

Navarro et al., 2016)

doi: 10.1210/clinem/dgab408 118 MaloneJTrautmannMWilhelmKTaylorKKendallDM

Clinical data shows a clear dose-response relationship, with higher doses producing significantly greater weight loss

The synthetic version is modified with a fatty acid side chain that binds to albumin in your blood, which extends the half-life to approximately 7 days