Hormonal decline is a natural part of aging, but the symptoms it causes hot flashes, brain fog, low libido, weight gain, poor sleep, mood instability are not inevitable
Second, IGF-1 stimulates angiogenesis, the formation of new blood vessels, which improves blood flow and oxygen delivery to the heart and other tissues
Due to its high solubility, amphipathic structure, and low molecular weight, melatonin displays a high intracellular and extracellular diffusion capacity, being able to cross cell membranes and the blood-brain barrier [6,15]
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MEL appears to counteract these effects by restoring complex I function and reducing markers of oxidative damage in plasma [66]