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The two medicines are considered Bioequivalent only when the results of bioequivalence testing are statistically within a set value range in terms of peak plasma concentration and time to reach peak plasma concentration

Direct stimulation of these receptors may contribute to nausea and emesis, particularly during the initial weeks of treatment or following dose escalation

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doi: 10.1016/j.kint.2019.04.033 109 ZhangPLuKXiaH

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