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LKB1-AMPK axis negatively regulates ferroptosis by inhibiting fatty acid synthesis

doi: 10.1016/j.bbamcr.2016.09.012 53 QinJGuoSYangJQaziIHPanBLvTet al

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Mito-apocynin (Mito-Apo), a mitochondria-targeted derivative of apocynin, concentrates at the inner mitochondrial membrane to inhibit NOX2 directly, where ROS production is highest

This study, performed at 1.5T, showed a decrease in creatine, consistent with abnormal energy metabolism [20]

The BCKDH kinase and phosphatase integrate BCAA and lipid metabolism via regulation of ATP-citrate Lyase