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The details of the analysis performed to obtain the MSD of the beads are described elsewhere ( 64 )

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The precautionary principle guides this recommendation given the serious nature of MTC and the availability of alternative therapeutic options

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7,8 HARMONY Outcomes was a randomised controlled trial of the long-acting GLP-1 receptor agonist (GLP-1RA) albiglutide (which is not commercially available) against placebo in 9,463 patients with type 2 diabetes and established cardiovascular disease