In 2024, the FDA expanded the label to include reducing the risk of major cardiovascular events in adults with established cardiovascular disease and overweight or obesity based on the SELECT trial, which randomized 17,604 patients and showed a 20% reduction in major adverse cardiovascular events over a mean 40 months
Semaglutide works by activating the GLP-1 receptor, helping regulate appetite and blood sugar
Notably, the same meta-analysis highlighted that liraglutide, particularly when compared to higher doses of semaglutide or tirzepatide, promoted weight loss without a clinically meaningful reduction in lean mass [77]
Once B 12 reserves reach normal levels, injections of vitamin B 12 will be needed every one to three months to prevent symptoms from returning
Who Should Not Take Wegovy
Its great to see how this aligns with the Pivot to Growth strategy and strengthens the complex generics portfolio