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Supporting our results, pharmacological interventions with other NAD + precursors including nicotinamide riboside (NR), nicotinamide mononucleotide (NMN), and stimulation of autophagy with rapamycin show anti-senescence properties and autophagic reactivation [69, 70]

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FUJIFILM Wako Pure Chemical Corporation, Osaka, Japan) were intraperitoneally administered, and atipamezole (2.5 mg/kg body weight

In Phase 2b with human patients, the oral route was not confirmed