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Unlike the traditional one drug-one target-one disease paradigm, network-based drug discovery reveals disease mechanisms from a holistic perspective, fully considering the complexity of biological systems [10]

However, serum IGF-1 values in both groups are indistinguishable by the age of 40

D-ribose also increased drug uptake approximately 2-fold and increased the lethality of gentamicin in drug-resistant Salmonella spp 46

At the same time, BSO does not have a significant effect on FAC-induced mitochondrial LPO

Those evidence highlight the role of glutaminolysis-PHD-mTORC1 axis in cancer growth