Previously, we showed that TG2 mediates crystallin, caspase 3, and collagen crosslinking in response to oxidative stress, hypoxic stress, and DNA damage, which leads to cataract formation, apoptotic resistance, and fibrotic development, respectively 4,5,6
It underscores the drugs potential potency and the imperative of its judicious use
Supports to detoxify the liver
Management should follow standard GORD advice in line with NICE CG184, starting with dietary and lifestyle changes such as eating smaller meals, avoiding trigger foods, and not lying down after eating
In some cases, these common injuries even develop into more serious issues, like arthritis
Contraindications include personal or family history of medullary thyroid cancer, multiple endocrine neoplasia type 2, severe kidney disease, or active pancreatitis