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Functional considerations like eyelid position, orbicularis tone, and preexisting asymmetry should also guide treatment planning

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KD may modulate the gut microbiota, which may be vital in some inflammatory skin diseases

Lentiviral-based transfection into HaCaT cells For suppression of NRF2 in HaCaT cells, lentiviral particles expressing shRNAs against human NRF2 were used to downregulate NRF2 mRNA

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In contrast, ATTR-CM, which arises from gain-of-function mutations, 260 has been the focus of all three therapeutic approaches, with multiple candidates already in clinical development (Fig