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The brain is remarkably sensitive to peptide signaling, which is why fatigue can be such a prominent early effect of GLP-1 agonist therapy

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Neurodegeneration triggers peripheral immune cell recruitment into the forebrain

(1990s)

While the early bellwether trials in the GLP-1 MDL are expected to influence the broader litigation landscape and may pave the way for settlements, the vision loss lawsuit is a separate entity

Diabetologia 62 , 136146 (2019)