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Appendices Appendix 1: Literature Search Strategies Literature Search - Vitamin B12 Economic Evidence-Based Analysis Search date: June 3, 2013 Databases searched: OVID MEDLINE, MEDLINE In-Process and Other Non-Indexed Citations, EMBASE

Energy and Metabolism Enhancement One big advantage of B12 injections is boosting energy and metabolism

There's no safety data for use during pregnancy or lactation

Nonclinical studies in rodents of clinically relevant doses of GLP-1 receptor agonists showed dose-related and treatment-duration-dependent increases in the incidence of thyroid C-cell tumors (adenomas and carcinomas)

Look for better symptoms, more energy, and feeling better overall

Keep reading to discover how vitamin B12 shots might fit into a weight loss plan and what other steps you can take to achieve your health goals