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Description

Patients with heart failure with reduced ejection fraction experienced a 35% reduction in major cardiovascular events (hazard ratio 0.65, 95% CI 0.49-0.87), while those with heart failure with preserved ejection fraction saw a 31% reduction (hazard ratio 0.69, 95% CI 0.51-0.91)

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Because it is a newer, patent-protected drug, there is currently no cheap generic version available, and experts don't expect one until the early 2030s

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Therefore, the full texts of 13 studies were assessed for eligibility, of which 6 studies were considered eligible for inclusion in our meta-analysis (Malaguarnera et al., 2002

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