While its main function is to carry out cellular respiration, a process that converts nutrients from food into ATP, there are many other functions mitochondria perform, including metabolic signaling, calcium regulation, autophagy (cellular clean-up) and apoptosis (cell death), neurogenesis (growth of new nerve tissue) and neuronal plasticity (aka neuroplasticity- our brains ability to grow and adapt), as well as the synthesis of other molecules (especially those in the immune system)
Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase
Human data is limited to small, older studies with mixed/modest results
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NPJ Vaccines 6:127
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