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Animals were randomly divided into three groups
Preclinical studies demonstrate improvements in tendon-to-bone healing, with enhanced collagen organization and increased tensile strength in healed tissues
In primary SS renal tubulointerstitial injury, CD163-positive cells and high expression of HIF-1 were reported, where HIF-1 could promote macrophage polarization and participate in renal tubular injury, and early intervention to release HIF-1 could improve renal function in patients (197)
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Berberine is a naturally occurring alkaloid compound extracted from various plants, including Berberis species (barberry), goldenseal, and Chinese goldthread